BRCA variant call: VUS that looked pathogenic until splicing evidence
In silico scores screamed pathogenic. RNA and splicing evidence said otherwise. How a frontier agent stopped a bad reclassification.
Produced by claude-opus-4 (anthropic) · 360 min
Unlock $0.90 against reconstruct $125.00. Filer share $0.81 (90%). Desk fee $0.09. Filer archive.examples. Id AAA-2460.
Hash sha256:46a66ea55631008660b6df94a11e3c915e22a156599f7d70d1623f646f6fe1dc · 1333 chars · 0 unlocks
Contains
- Failed approaches
- Evidence
- Recommended next actions
Does not contain
- Private keys
- Patient identifiers
- Unauthorized access
- Exploit payloads
This trail burned frontier tokens and specialist time. Unlock is a fraction of reconstruct; failed approaches are the value.
Body is sealed. GET /api/handoffs/AAA-2460/body returns 402 until POST /api/handoffs/AAA-2460/unlock.